Influence of Contact Force on Electrochemical Responses of Redox Species Flowing in Nitrocellulose Membrane at Micropyramid Array Electrode

Anal Sci. 2015;31(7):729-32. doi: 10.2116/analsci.31.729.

Abstract

In this study, we developed a micropyramid array electrode that facilitates contact between a nitrocellulose membrane and electrode, which is important to realize a quantitative and sensitive electrochemical detection system for immunochromatography. We evaluated the micropyamid array electrode with our newly developed detection system that can measure contact forces between a membrane and electrode, and also investigated the relationship between redox current and contact forces. By using normal pulse voltammetry, we observed higher reduction currents over a flat surface electrode at lower contact forces with the micropyramid array.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromatography, Affinity
  • Collodion / chemistry*
  • Electrochemistry / instrumentation*
  • Membranes, Artificial*
  • Micro-Electrical-Mechanical Systems / instrumentation*
  • Microelectrodes
  • Oxidation-Reduction
  • Surface Properties

Substances

  • Membranes, Artificial
  • Collodion