Multifunctional Fluorescent-Magnetic Polymeric Colloidal Particles: Preparations and Bioanalytical Applications

ACS Appl Mater Interfaces. 2015 Oct 28;7(42):23373-86. doi: 10.1021/acsami.5b07515. Epub 2015 Oct 13.

Abstract

Fluorescent-magnetic particles (FMPs) play important roles in modern materials, especially as nanoscale devices in the biomedical field. The interesting features of FMPs are attributed to their dual detection ability, i.e., fluorescent and magnetic modes. Functionalization of FMPs can be performed using several types of polymers, allowing their use in various applications. The synergistic potentials for unique multifunctional, multilevel targeting nanoscale devices as well as combination therapies make them particularly attractive for biomedical applications. However, the synthesis of FMPs is challenging and must be further developed. In this review article, we summarized the most recent representative works on polymer-based FMP systems that have been applied particularly in the bioanalytical field.

Keywords: bioanalytical applications; fluorophore; hybrid nanoparticle; magnetic nanoparticle; multifunctional devices.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Colloids / chemistry
  • Colloids / therapeutic use
  • Drug Delivery Systems
  • Fluorescence
  • Humans
  • Magnetics
  • Nanoparticles / chemistry*
  • Nanoparticles / therapeutic use
  • Nanotechnology*
  • Polymers / chemistry*
  • Polymers / therapeutic use

Substances

  • Colloids
  • Polymers