Evidence for zoonotic origins of Middle East respiratory syndrome coronavirus

J Gen Virol. 2016 Feb;97(2):274-280. doi: 10.1099/jgv.0.000342. Epub 2015 Nov 13.

Abstract

Middle East respiratory syndrome (MERS) is an emerging infectious disease, caused by Middle East respiratory syndrome coronavirus (MERS-CoV) and is considered to be a zoonosis. However, the natural reservoirs of MERS-CoV remain obscure, with bats and camels as the most suspected sources. In this article, we review the evidence supporting a bat/camel origin of human MERS-CoV infection and current knowledge on the modes of camel-to-human transmission of MERS-CoV.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Camelus*
  • Chiroptera*
  • Communicable Diseases, Emerging / epidemiology*
  • Communicable Diseases, Emerging / transmission
  • Communicable Diseases, Emerging / virology
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / transmission
  • Coronavirus Infections / virology
  • Disease Reservoirs*
  • Disease Transmission, Infectious
  • Humans
  • Middle East Respiratory Syndrome Coronavirus / isolation & purification*
  • Zoonoses / epidemiology*
  • Zoonoses / transmission
  • Zoonoses / virology