Report of the Inaugural Meeting of the TFOS i(2) = initiating innovation Series: Targeting the Unmet Need for Dry Eye Treatment

Wendy Chao; Carlos Belmonte; José M Benitez Del Castillo; Anthony J Bron; Harminder S Dua; Kelly K Nichols; Gary D Novack; Stefan Schrader; Mark D Willcox; James S Wolffsohn; David A Sullivan

doi:10.1016/j.jtos.2015.11.003

Report of the Inaugural Meeting of the TFOS i(2) = initiating innovation Series: Targeting the Unmet Need for Dry Eye Treatment

Ocul Surf. 2016 Apr;14(2):264-316. doi: 10.1016/j.jtos.2015.11.003. Epub 2016 Jan 14.

Authors

Affiliations

¹ Schepens Eye Research Institute, Massachusetts Eye and Ear and Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
² Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas, and International Brain Research Organization, Alicante, Spain.
³ Complutense University of Madrid and Hospital Clinico San Carlos, Madrid, Spain.
⁴ University of Oxford, Oxford, UK.
⁵ Section of Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK.
⁶ School of Optometry, University of Alabama, Birmingham, AL, USA.
⁷ PharmaLogic Development, Inc., San Rafael, CA, USA.
⁸ Laboratory for Experimental Ophthalmology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
⁹ School of Optometry and Vision Science, University of New South Wales, Sydney, NSW, Australia.
¹⁰ Ophthalmic Research Group, Life and Health Sciences, Aston University, Birmingham, UK.
¹¹ Schepens Eye Research Institute, Massachusetts Eye and Ear and Department of Ophthalmology, Harvard Medical School, Boston, MA, USA. Electronic address: david.sullivan@schepens.harvard.edu.

PMID: 26774910
DOI: 10.1016/j.jtos.2015.11.003

Abstract

On March 21, 2015, a meeting was held in London, United Kingdom, to address the progress in targeting the unmet need for dry eye disease (DED) treatment. The meeting, which launched the i(2) = initiating innovation series, was sponsored by the Tear Film & Ocular Surface Society (TFOS; www.TearFilm.org) and supported by Dompé. The TFOS i(2) meeting was designed to review advances in the understanding of DED since publication of the 2007 TFOS International Dry Eye WorkShop (DEWS) report, and to help launch the highly anticipated sequel, DEWS II. The meeting was structured to discuss the scope of the DED problem, to review the clinical challenges of DED, and to consider the treatment challenges of DED. This article provides a synopsis of the presentations of this TFOS i(2) meeting.

Keywords: Clinical trials; Dry Eye WorkShop II (DEWS II); Tear Film & Ocular Surface Society; drug development; dry eye disease (DED); i(2) = initiating innovation series.

Publication types

Congress

MeSH terms

Dry Eye Syndromes*
Eye
Humans
Keratoconjunctivitis Sicca
Societies, Medical
Tears