Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression

Blood. 2016 May 26;127(21):2641-4. doi: 10.1182/blood-2016-02-696922. Epub 2016 Mar 22.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Survival
  • Gene Expression Regulation
  • Germ-Line Mutation
  • Humans
  • Hypoxia / genetics
  • Hypoxia / metabolism
  • Hypoxia-Inducible Factor 1, alpha Subunit / genetics*
  • Hypoxia-Inducible Factor 1, alpha Subunit / metabolism
  • Mutation*
  • Neutrophils / cytology*
  • Neutrophils / metabolism
  • Oxidative Stress
  • Succinate Dehydrogenase / genetics*
  • Succinate Dehydrogenase / metabolism
  • Succinic Acid / metabolism

Substances

  • Hypoxia-Inducible Factor 1, alpha Subunit
  • SDHD protein, human
  • Succinic Acid
  • Succinate Dehydrogenase