Abstract
We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [(68)Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control. The system achieved a far superior signal-to-noise ratio compared to conventional sodium iodide-based radio-HPLC detection and allowed real-time visualisation of positrons in the monolith.
MeSH terms
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Chromatography, High Pressure Liquid
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Citrates / chemistry
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Gallium / chemistry
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Gallium Radioisotopes / chemistry
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Miniaturization
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Positron-Emission Tomography / standards*
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Quality Control
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Radiopharmaceuticals / chemistry*
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Signal-To-Noise Ratio
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Silicon Dioxide / chemistry*
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Sodium Iodide / chemistry
Substances
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Citrates
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Gallium Radioisotopes
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Radiopharmaceuticals
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Silicon Dioxide
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Gallium-68
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Gallium
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Sodium Iodide
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gallium citrate