Endoscopic biodegradable biliary stents in the treatment of benign biliary strictures: First report of clinical use in patients

Dig Endosc. 2017 Jan;29(1):118-121. doi: 10.1111/den.12709. Epub 2016 Sep 22.

Abstract

The first clinical experience of endoscopically inserted polydioxanone biodegradable biliary stents (BDBS) in the treatment of benign biliary strictures is reported. Two patients with a benign common bile duct stricture were endoscopically treated with 8-mm-bore BDBS during endoscopic retrograde cholangiography. Both BDBS insertions were technically successful and without adverse events. At 6 months, the stricture resolution was excellent and BDBS degradation was predicted in repeated magnetic resonance imaging. The first experience with endoscopic BDBS seems promising in the treatment of benign biliary strictures. During 6 months of follow up, BDBS seemed sufficient for remodeling and resolution of strictures. Further studies are needed to confirm the effectiveness of biodegradable biliary stents in endoscopic management of benign biliary strictures.

Keywords: Biliary stent; ERCP; bioabsorbable; biodegradable.

Publication types

  • Case Reports

MeSH terms

  • Absorbable Implants*
  • Cholestasis, Extrahepatic / diagnosis
  • Cholestasis, Extrahepatic / surgery*
  • Common Bile Duct / diagnostic imaging
  • Common Bile Duct / surgery*
  • Digestive System Surgical Procedures / methods*
  • Humans
  • Magnetic Resonance Imaging / methods
  • Prosthesis Design
  • Stents*
  • Tomography, X-Ray Computed