Refinements in Sarcoma Classification in the Current 2013 World Health Organization Classification of Tumours of Soft Tissue and Bone

Surg Oncol Clin N Am. 2016 Oct;25(4):621-43. doi: 10.1016/j.soc.2016.05.001. Epub 2016 Jul 30.

Abstract

The fourth edition of the World Health Organization (WHO) Classification of Tumours of Soft Tissue and Bone was published in February 2013. The 2013 WHO volume provides an updated classification scheme and reproducible diagnostic criteria, which are based on recent clinicopathologic studies and genetic and molecular data that facilitated refined definition of established tumor types, recognition of novel entities, and the development of novel diagnostic markers. This article reviews updates and changes in the classification of bone and soft tissue tumors from the 2002 volume.

Keywords: Bone; Classification; Histology; Sarcoma; Soft tissue; Tumor; World Health Organization.

Publication types

  • Review

MeSH terms

  • Humans
  • Practice Guidelines as Topic*
  • Sarcoma / classification*
  • Sarcoma / genetics
  • Sarcoma / pathology*
  • Soft Tissue Neoplasms / classification*
  • Soft Tissue Neoplasms / genetics
  • Soft Tissue Neoplasms / pathology*
  • Terminology as Topic*
  • World Health Organization