3D-printed Microfluidic Devices: Fabrication, Advantages and Limitations-a Mini Review

Anal Methods. 2016 Aug 21;8(31):6005-6012. doi: 10.1039/C6AY01671E. Epub 2016 Jul 27.

Abstract

A mini-review with 79 references. In this review, the most recent trends in 3D-printed microfluidic devices are discussed. In addition, a focus is given to the fabrication aspects of these devices, with the supplemental information containing detailed instructions for designing a variety of structures including: a microfluidic channel, threads to accommodate commercial fluidic fittings, a flow splitter; a well plate, a mold for PDMS channel casting; and how to combine multiple designs into a single device. The advantages and limitations of 3D-printed microfluidic devices are thoroughly discussed, as are some future directions for the field.