Efficient Healing Takes Some Nerve: Electrical Stimulation Enhances Innervation in Cutaneous Human Wounds

J Invest Dermatol. 2017 Mar;137(3):543-545. doi: 10.1016/j.jid.2016.10.018.

Abstract

Cutaneous nerves extend throughout the dermis and epidermis and control both the functional and reparative capacity of the skin. Denervation of the skin impairs cutaneous healing, presenting evidence that nerves provide cues essential for timely wound repair. Sebastian et al. demonstrate that electrical stimulation promotes reinnervation and neural differentiation in human acute wounds, thus accelerating wound repair.

Publication types

  • Comment

MeSH terms

  • Electric Stimulation
  • Epidermis
  • Humans
  • Skin / innervation*
  • Skin Diseases
  • Wound Healing*