Molecular characterization of Camelpox virus isolates from Bikaner, India: Evidence of its endemicity

Acta Trop. 2017 Jul:171:1-5. doi: 10.1016/j.actatropica.2017.03.011. Epub 2017 Mar 14.

Abstract

Camelpox is an important viral disease of camels, which may produce mild skin lesions or severe systemic infections. Camelpox virus (CMLV) isolates retrieved from an incidence of camelpox in camels at Bikaner, India were characterized on the basis of genotype and pathotype. Histopathological examination of the CMLV scab revealed intracytoplasmic-eosinophilic inclusion bodies. The phylogenetic analysis of all eight CMLV isolates for C18L gene nucleotide sequence revealed its clustering with its strains M-96 from Kazakhstan and CMS from Iran. The study will help to understand the transmission chain, pathobiology, and epidemiology of circulating CMLV strains. The full genome sequencing of some of the exemplary samples of CMLV is recommended in order to plan and implement a suitable control strategy.

Keywords: Camelpox; Histopathology; Isolation; PCR; Phylogenetic.

MeSH terms

  • Animals
  • Base Sequence
  • Camelus / virology*
  • India / epidemiology
  • Orthopoxvirus / genetics*
  • Orthopoxvirus / isolation & purification*
  • Phylogeny
  • Poxviridae Infections / veterinary*
  • Poxviridae Infections / virology
  • Skin Diseases / epidemiology
  • Skin Diseases / veterinary*
  • Skin Diseases / virology