Abstract
Three new isoaigialones, A, B, and C (1-3), along with aigialone (4), were isolated from the crude EtOAc extract of a Phaeoacremonium sp., an endophytic fungus obtained from the leaves of Senna spectabilis. The structures of these compounds were elucidated based on the analysis of spectroscopic data. Compounds 2 and 4 were active against the phytopathogenic fungi Cladosporium cladosporioides and C. sphaerospermum. This is the first report of metabolites produced by an Phaeoacremonium sp., associated with S. spectabilis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetals / chemistry
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Acetals / isolation & purification*
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Acetals / pharmacology*
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Antifungal Agents / chemistry
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Antifungal Agents / isolation & purification*
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Antifungal Agents / pharmacology*
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Ascomycota / chemistry*
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Cladosporium / chemistry*
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Ketones / chemistry
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Ketones / isolation & purification*
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Ketones / pharmacology*
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Lactones / chemistry
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Lactones / isolation & purification*
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Lactones / metabolism
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Lactones / pharmacology
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Molecular Structure
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Plant Leaves / chemistry*
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Senna Plant / chemistry*
Substances
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Acetals
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Antifungal Agents
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Ketones
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Lactones
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aigialone
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isoaigialone A
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isoaigialone B
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isoaigialone C