Two new Co(II) complexes of 4-((3-ethoxy-2-hydroxybenzylidene)amino)-N-(thiazol-2-yl)benzenesulphonamide and 4-((pyridin-2-ylmethylene)amino)-N-(thiazol-2-yl)benzene sulfonamide were synthesised. The structure of the complexes was identified by elemental analysis, FT-IR, electronic, EI mass, Powder XRD spectra and magnetic moment. The TG and DTA patterns of the complexes were supported the structures. The fluorescence quenching of these complexes with alizarin dye were premeditated and the free energy change (∆Get) for electron transfer process was designed by Rehm-Weller equation. The [Co(L1-H)2(H2O)2] and [Co(L2)2(H2O)2].2H2O were submitted for in vitro cytotoxicity studies in human breast cancer cell line (MCF 7).
Keywords: Co(II) complexes; Fluorescence properties; In vitro cytotoxicity; Rehm–Weller equation.