Cyclic Polymers: From Scientific Curiosity to Advanced Materials for Gene Delivery and Surface Modification

Bart Verbraeken; Richard Hoogenboom

doi:10.1002/anie.201703418

Cyclic Polymers: From Scientific Curiosity to Advanced Materials for Gene Delivery and Surface Modification

Angew Chem Int Ed Engl. 2017 Jun 12;56(25):7034-7036. doi: 10.1002/anie.201703418. Epub 2017 May 3.

Authors

Bart Verbraeken¹, Richard Hoogenboom¹

Affiliation

¹ Supramolecular Chemistry Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, 9000, Ghent, Belgium.

PMID: 28467027
DOI: 10.1002/anie.201703418

Abstract

Cyclic versus linear: The superiority of cyclic polymers over their linear counterparts is highlighted. Cyclic poly(2-oxazoline)s have been shown to provide excellent shielding properties when grafted to TiO₂ surfaces and Fe₃ O₄ nanoparticles owing to their ultrahigh grafting densities leading to low friction surfaces, superior antifouling properties, and extreme nanoparticle stabilization.

Keywords: cyclic polymers; nanoparticles; poly(2-oxazoline)s; surface chemistry; topological effects.

MeSH terms

Cyclization
Ferrosoferric Oxide / chemistry
Gene Transfer Techniques*
Metal Nanoparticles / chemistry
Polymers / chemistry*
Surface Properties
Titanium / chemistry

Substances

Polymers
titanium dioxide
Titanium
Ferrosoferric Oxide