Designer Probiotics: Paving the Way to Living Therapeutics

Trends Biotechnol. 2017 Aug;35(8):679-682. doi: 10.1016/j.tibtech.2017.04.001. Epub 2017 May 5.

Abstract

Enhancing the functional repertoire of probiotics is a promising approach to cope with the inexorable rise of antibiotic-resistant pathogens and the rather slow development of new antibiotics. Probiotics that deliver novel therapeutics efficiently and with site specificity are emerging living therapeutics that may transform existing paradigms of disease diagnosis and prevention.

Keywords: biotherapeutics; mucosal vaccines; recombinant probiotics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Drug Design*
  • Humans
  • Probiotics / therapeutic use*