Neurodegenerative drug discovery: building on the past, looking to the future

Future Med Chem. 2017 May;9(8):707-709. doi: 10.4155/fmc-2017-0087. Epub 2017 May 15.
No abstract available

Keywords: acetylcholinesterase inhibitors; drug discovery; monoamine oxidase inhibitors; multitarget directed ligands; natural antioxidants; neurodegenerative diseases; phosphodiesterase inhibitors; polypharmacology; proteinopathies; serotonin receptors; small molecules; target-based approach.

Publication types

  • Introductory Journal Article

MeSH terms

  • Antioxidants / therapeutic use
  • Cholinesterase Inhibitors / therapeutic use
  • Drug Discovery*
  • Humans
  • Monoamine Oxidase Inhibitors / therapeutic use
  • Neurodegenerative Diseases / drug therapy
  • Neurodegenerative Diseases / pathology*
  • Phosphodiesterase Inhibitors / therapeutic use
  • Small Molecule Libraries / chemistry
  • Small Molecule Libraries / therapeutic use

Substances

  • Antioxidants
  • Cholinesterase Inhibitors
  • Monoamine Oxidase Inhibitors
  • Phosphodiesterase Inhibitors
  • Small Molecule Libraries