Visible-Light-Driven Carboxylation of Aryl Halides by the Combined Use of Palladium and Photoredox Catalysts

Katsuya Shimomaki; Kei Murata; Ruben Martin; Nobuharu Iwasawa

doi:10.1021/jacs.7b04838

Visible-Light-Driven Carboxylation of Aryl Halides by the Combined Use of Palladium and Photoredox Catalysts

J Am Chem Soc. 2017 Jul 19;139(28):9467-9470. doi: 10.1021/jacs.7b04838. Epub 2017 Jul 5.

Authors

Katsuya Shimomaki¹, Kei Murata¹, Ruben Martin^{2

3}, Nobuharu Iwasawa¹

Affiliations

¹ Department of Chemistry, Tokyo Institute of Technology , O-okayama, Meguro-ku, Tokyo 152-8551, Japan.
² Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av. Països Catalans 16, 43007 Tarragona, Spain.
³ Catalan Institution for Research and Advanced Studies (ICREA) , Passeig Lluïs Companys, 23, 08010, Barcelona, Spain.

PMID: 28657743
DOI: 10.1021/jacs.7b04838

Abstract

A highly useful, visible-light-driven carboxylation of aryl bromides and chlorides with CO₂ was realized using a combination of Pd(OAc)₂ as a carboxylation catalyst and Ir(ppy)₂(dtbpy)(PF₆) as a photoredox catalyst. This carboxylation reaction proceeded in high yields under 1 atm of CO₂ with a variety of functionalized aryl bromides and chlorides without the necessity of using stoichiometric metallic reductants.

Publication types

Research Support, Non-U.S. Gov't