Structural and biological diversity of natural p-terphenyls

J Asian Nat Prod Res. 2018 Jan;20(1):1-13. doi: 10.1080/10286020.2017.1381089. Epub 2017 Oct 13.

Abstract

p-Terphenyls consisting of a C-18 tricyclic or polycyclic C-18 aromatic skeleton, have diverse structures because of the variation of the middle ring and the connections between the rings, and to the main skeleton. p-Terphenyls have recently been found to exhibit various biological activities such as cytotoxic, α-glucosidase inhibitory, antioxidant, and antimicrobial activity. In this review, we briefly summarized the structural varieties, biosyntheses, and bioactivities of natural p-terphenyl derivatives referring to the recent 10 years' publications.

Keywords: bioactivity; biosynthesis; isolation; p-terphenyl.

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / pharmacology*
  • Biodiversity
  • Biological Products / chemistry
  • Biological Products / pharmacology
  • Glycoside Hydrolase Inhibitors / chemistry
  • Glycoside Hydrolase Inhibitors / pharmacology
  • Molecular Structure
  • Terphenyl Compounds / chemistry*
  • Terphenyl Compounds / pharmacology*
  • alpha-Glucosidases / metabolism*

Substances

  • Antioxidants
  • Biological Products
  • Glycoside Hydrolase Inhibitors
  • Terphenyl Compounds
  • alpha-Glucosidases