Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes

Glycobiology. 2018 Dec 1;28(1):3-8. doi: 10.1093/glycob/cwx089.

Abstract

CAZypedia was initiated in 2007 to create a comprehensive, living encyclopedia of the carbohydrate-active enzymes (CAZymes) and associated carbohydrate-binding modules involved in the synthesis, modification and degradation of complex carbohydrates. CAZypedia is closely connected with the actively curated CAZy database, which provides a sequence-based foundation for the biochemical, mechanistic and structural characterization of these diverse proteins. Now celebrating its 10th anniversary online, CAZypedia is a successful example of dynamic, community-driven and expert-based biocuration. CAZypedia is an open-access resource available at URL http://www.cazypedia.org.

Keywords: biocuration; bioinformatics; carbohydrate-active enzymes; glycobiology; glycoscience.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbohydrates / chemistry*
  • Carbohydrates / history
  • Databases, Protein
  • Esterases / chemistry
  • Esterases / history
  • Esterases / metabolism*
  • Glycosyltransferases / chemistry
  • Glycosyltransferases / history
  • Glycosyltransferases / metabolism*
  • History, 21st Century
  • Polysaccharide-Lyases / chemistry
  • Polysaccharide-Lyases / history
  • Polysaccharide-Lyases / metabolism*

Substances

  • Carbohydrates
  • Glycosyltransferases
  • Esterases
  • Polysaccharide-Lyases