Mechanical Signaling and Extracellular Matrix in Uterine Fibroids

Semin Reprod Med. 2017 Nov;35(6):487-493. doi: 10.1055/s-0037-1607268. Epub 2017 Nov 3.

Authors

Saima Rafique¹, James H Segars², Phyllis C Leppert³

Affiliations

¹ Department of Obstetrics and Gynecology, Howard University Hospital, Washington, District of Columbia.
² Howard W. and Georgeanna Seegar Jones Laboratory of Reproductive Sciences and Women's Health Research, Department of Obstetrics and Gynecology, Johns Hopkins Medical University, Baltimore, Maryland.
³ Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, North Carolina.

PMID: 29100236
DOI: 10.1055/s-0037-1607268

No abstract available

Publication types

Review

MeSH terms

Apoptosis
Extracellular Matrix / metabolism*
Extracellular Matrix / pathology
Female
Gene Expression Regulation, Neoplastic
Humans
Leiomyoma / metabolism*
Leiomyoma / pathology
Leiomyoma / therapy
Leiomyomatosis / metabolism*
Leiomyomatosis / pathology
Leiomyomatosis / therapy
Mechanotransduction, Cellular*
Models, Biological*
Stress, Mechanical
Therapies, Investigational / trends
Tumor Burden
Uterine Neoplasms / metabolism*
Uterine Neoplasms / pathology
Uterine Neoplasms / therapy
Uterus / metabolism*
Uterus / pathology