Investigation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with tinnitus

J Laryngol Otol. 2018 Feb;132(2):129-132. doi: 10.1017/S0022215117002481. Epub 2018 Jan 15.

Abstract

Objective: This study aimed to evaluate patients with tinnitus in terms of mean platelet volume and platelet distribution width, and to explore neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, recently reported in the literature as being possible inflammation markers.

Methods: This study comprised 64 tinnitus patients and 64 age-matched healthy controls. Statistical significance level was accepted as p < 0.05.

Results: Mean platelet volume (t = 3.245, p = 0.002) and platelet distribution width (Z = 3.945, p < 0.001) were significantly higher in the patient group than the control group.

Conclusion: The results suggest that a prothrombotic condition might play a role in the pathophysiology of tinnitus.

Keywords: Clinical Marker; Inflammation; Mean Platelet Volume; Thrombosis; Tinnitus.

MeSH terms

  • Adult
  • Aged
  • Biomarkers / blood
  • Blood Platelets / pathology*
  • Case-Control Studies
  • Contrast Media
  • Female
  • Humans
  • Lymphocyte Count
  • Lymphocytes / pathology*
  • Magnetic Resonance Imaging / methods
  • Male
  • Mean Platelet Volume*
  • Middle Aged
  • Neutrophils / pathology*
  • Predictive Value of Tests
  • Prospective Studies
  • Sensitivity and Specificity
  • Temporal Bone / diagnostic imaging
  • Tinnitus / blood*
  • Tinnitus / diagnosis*

Substances

  • Biomarkers
  • Contrast Media