Exercise Intervention: Attrition, Compliance, Adherence, and Progression Following Hematopoietic Stem Cell Transplantation

Clin J Oncol Nurs. 2018 Feb 1;22(1):97-103. doi: 10.1188/18.CJON.97-103.

Abstract

Background: Exercise is widely touted as an effective intervention to optimize health and well-being after high-dose chemotherapy and hematopoietic stem cell transplantation. .

Objectives: This article reports attrition, compliance, adherence, and progression from the strength training arm of the single-blind randomized, controlled trial Strength Training to Enhance Early Recovery (STEER). .

Methods: 37 patients were randomized to the intervention and participated in a structured strength training program introduced during hospitalization and continued for six weeks after release. Research staff and patients maintained exercise logs to document compliance, adherence, and progression. .

Findings: No patients left the study because of burden. Patients were compliant with completion of exercise sessions, and their adherence was high; they also progressed on their exercise prescription. Because STEER balances intervention effectiveness with patient burden, the findings support the likelihood of successful translation into clinical practice.

Keywords: adherence; attrition; compliance; hematopoietic stem cell transplantation; progression.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Exercise Therapy / methods*
  • Fatigue / etiology*
  • Fatigue / therapy*
  • Female
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Hematopoietic Stem Cell Transplantation / psychology*
  • Humans
  • Male
  • Middle Aged
  • Patient Compliance / psychology*
  • Patient Compliance / statistics & numerical data*
  • Quality of Life
  • Random Allocation
  • United States