Comparison of tissue oximeters on a liquid phantom with adjustable optical properties: an extension

S Kleiser; D Ostojic; B Andresen; N Nasseri; H Isler; F Scholkmann; T Karen; G Greisen; M Wolf

doi:10.1364/BOE.9.000086

Comparison of tissue oximeters on a liquid phantom with adjustable optical properties: an extension

Biomed Opt Express. 2017 Dec 5;9(1):86-101. doi: 10.1364/BOE.9.000086. eCollection 2018 Jan 1.

Authors

S Kleiser¹, D Ostojic¹, B Andresen², N Nasseri^{1

3}, H Isler¹, F Scholkmann^{1

3}, T Karen⁴, G Greisen², M Wolf¹

Affiliations

¹ Biomedical Optics Research Laboratory, Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
² Department of Neonatology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
³ Institute of Complementary Medicine, University of Bern, Bern, Switzerland.
⁴ Department of Neonatology, University Hospital Zurich, Zurich, Switzerland.

Abstract

Cerebral near-infrared spectroscopy (NIRS) oximetry may help clinicians to improve patient treatment. However, the application of NIRS oximeters is increasingly causing confusion to the users due to the inconsistency of tissue oxygen haemoglobin saturation (StO₂) readings provided by different oximeters. To establish a comparability of oximeters, in our study we performed simultaneous measurements on the liquid phantom mimicking properties of neonatal heads and compared the tested device to a reference NIRS oximeter (OxiplexTS). We evaluated the NIRS oximeters FORE-SIGHT, NIRO and SenSmart, and reproduced previous results with the INVOS and OxyPrem v1.3 oximeters. In general, linear relationships of the StO₂ values with respect to the reference were obtained. Device specific hypoxic and hyperoxic thresholds (as used in the SafeBoosC study, www.safeboosc.eu) and a table allowing for conversion of StO₂ values are provided.

Keywords: (120.3890) Medical optics instrumentation; (170.6510) Spectroscopy, tissue diagnostics.