Conjugated polymer nanoparticles-based fluorescent biosensor for ultrasensitive detection of hydroquinone

Anal Chim Acta. 2018 Jul 5:1012:60-65. doi: 10.1016/j.aca.2018.01.027. Epub 2018 Jan 24.

Abstract

This work describes a simple and sensitive fluorescent method for detection of hydroquinone utilizing conjugated polymer nanoparticles (CPNs). The CPNs serve both as a catalyst to accelerate the conversion of hydroquinone to benzoquinone and a fluorescent probe. In the presence of hydroquinone, the fluorescence of CPNs can be effectively quenched by benzoquinone. The detection limit of hydroquinone was down to 5 nM and excellent selectivity toward possible interferences was obtained. This method was successfully applied for hydroquinone detection in lake water and satisfactory results were achieved.

Keywords: Biosensor; Conjugated polymer nanoparticles; Fluorescence; Hydroquinone.

MeSH terms

  • Biosensing Techniques*
  • Fluorescence*
  • Fluorescent Dyes / chemistry*
  • Hydroquinones / analysis*
  • Microscopy, Fluorescence
  • Nanoparticles / chemistry*
  • Polymers / chemistry*

Substances

  • Fluorescent Dyes
  • Hydroquinones
  • Polymers