Valve performance classification in 630 subcoronary Ross patients over 22 years

J Thorac Cardiovasc Surg. 2018 Jul;156(1):79-86.e2. doi: 10.1016/j.jtcvs.2018.03.015. Epub 2018 Mar 12.

Abstract

Objective: To define the function of the "Ross valves" and its clinical meaning in a practical valve performance classification as part of the outcome analysis.

Methods: From 1994 to 2017, 630 consecutive patients underwent the subcoronary Ross procedure at our institution. The valve performance classification combines hemodynamics, symptoms, and management criteria. Median follow-up was 12.5 years (maximum 22.3 years, 7404 patient-years, 99.4% completeness).

Results: The mean age of the patients was 44.7 ± 11.9 years. Hospital deaths was 0.3% (n = 2). Twenty years after the operation survival was 73.1% (95% confidence interval [CI], 65.4%-81.6%) and statistically not different from the age- and gender-matched general population; freedom from reoperation was 85.9% (95% CI, 80.2%-92.0%; 0.6% per patient-year), 89.8% (95% CI, 84.3%-95.7%) for autograft, and 91.0% (95% CI, 86.3%-96.0%) for homograft. Preoperative annulus diameter, aortic regurgitation, annulus reinforcement, sinotubular junction reinforcement, and bicuspid aortic valve type were no significant risk factors for reoperation. At 20 years the probability of a patient being in valve performance class I to IV was 5%, 74%, 19%, and 1%, respectively. Time to reoperation was not different in bicuspid and tricuspid aortic valves; preoperative aortic stenosis tended to have better outcome of autograft function.

Conclusions: These up to 22 years data show that the subcoronary Ross procedure continues to provide an excellent tissue aortic valve replacement. The suggested valve performance classification emerged as a practical concept for outcome analysis with the probability of 79% being in the favorable class I or II at 20 years.

Keywords: Ross procedure; hemodynamics; long-term data; subcoronary technique; valve performance classification.

Publication types

  • Observational Study
  • Video-Audio Media

MeSH terms

  • Adult
  • Aortic Valve / diagnostic imaging
  • Aortic Valve / physiopathology
  • Aortic Valve / surgery*
  • Bioprosthesis*
  • Blood Vessel Prosthesis Implantation / adverse effects
  • Blood Vessel Prosthesis Implantation / instrumentation*
  • Blood Vessel Prosthesis Implantation / mortality
  • Blood Vessel Prosthesis*
  • Female
  • Hemodynamics
  • Hospital Mortality
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / mortality
  • Postoperative Complications / surgery
  • Progression-Free Survival
  • Prospective Studies
  • Prosthesis Design
  • Recovery of Function
  • Reoperation
  • Risk Factors
  • Time Factors
  • Young Adult