Naturally occurring cell adhesion inhibitors

J Nat Med. 2018 Sep;72(4):817-835. doi: 10.1007/s11418-018-1220-z. Epub 2018 May 19.

Abstract

This paper reviews naturally occurring cell adhesion inhibitors derived from a plant, microbial and marine origin. Plant-derived inhibitors are classified according to a type of structure. Microbially and marine-derived inhibitors were described according to age. In addition, effects of inhibitors on cell proliferation and that of standards on cell adhesion are listed as much as possible.

Keywords: Cell adhesion; HUVEC; ICAM-1; Inhibitor; LFA-1; LPS; Natural products; PMA; TNF-α.

Publication types

  • Review

MeSH terms

  • Biological Products
  • Cell Adhesion / drug effects*
  • Cell Adhesion Molecules / antagonists & inhibitors*
  • Humans

Substances

  • Biological Products
  • Cell Adhesion Molecules