Bile acid metabolism and signaling: potential therapeutic target for nonalcoholic fatty liver disease

Clin Transl Gastroenterol. 2018 Jun 29;9(6):164. doi: 10.1038/s41424-018-0034-3.

Authors

Chuan-Hao Lin¹, Rohit Kohli²

Affiliations

¹ Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital Los Angeles, and the Department of Pediatrics Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. chlin@chla.usc.edu.
² Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital Los Angeles, and the Department of Pediatrics Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

No abstract available

Publication types

Research Support, N.I.H., Extramural
Review

MeSH terms

Bile Acids and Salts / metabolism*
Carrier Proteins / antagonists & inhibitors
Enterohepatic Circulation
Humans
Membrane Glycoproteins / antagonists & inhibitors
Non-alcoholic Fatty Liver Disease / drug therapy*
Non-alcoholic Fatty Liver Disease / metabolism*
Receptors, Cytoplasmic and Nuclear / agonists
Signal Transduction*

Substances

Bile Acids and Salts
Carrier Proteins
Membrane Glycoproteins
Receptors, Cytoplasmic and Nuclear
bile acid binding proteins
farnesoid X-activated receptor

Grants and funding

R01 DK100314/DK/NIDDK NIH HHS/United States