Arbutus species (Ericaceae) as source of valuable bioactive products

Crit Rev Food Sci Nutr. 2019;59(6):864-881. doi: 10.1080/10408398.2018.1551777. Epub 2018 Dec 22.

Abstract

In addition to nutrients, plant foods contain compounds that may provide additional health benefits improving the quality of life. Species from Arbutus genus (Ericaceae) represent a promising source of healthy phytochemicals. Bioactive compounds including such as anthocyanins, iridoids, phenols, triterpenes, sterols, and fatty acids are reported from Arbutus species. Some Arbutus species revealed promising biological activities including antioxidant, anti-inflammatory, anti-proliferative, anti-diabetic, and antimicrobial activities, and deserve for that reason further consideration for new drug discovery. However, only few species are investigated scientifically for their chemical profile and biological activities. The aim of this article is to summarize the current knowledge of the components and biological properties of Arbutus species common in Mediterranean area, as well as the future prospects on their applications as potentially valuable products.

Keywords: Mediterranean; biological properties; chemical constituents; functional products.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Infective Agents / analysis
  • Anti-Infective Agents / pharmacology
  • Anti-Inflammatory Agents / analysis
  • Anti-Inflammatory Agents / pharmacology
  • Antioxidants / analysis
  • Antioxidants / pharmacology
  • Cardiovascular Diseases / drug therapy
  • Cell Line, Tumor
  • Ericaceae / chemistry*
  • Fruit / chemistry
  • Humans
  • Hypoglycemic Agents / analysis
  • Hypoglycemic Agents / pharmacology
  • Phenols / analysis
  • Phenols / pharmacology
  • Phytochemicals / analysis*
  • Phytochemicals / pharmacology*
  • Phytosterols / analysis
  • Phytosterols / pharmacology
  • Plant Extracts / analysis*
  • Plant Extracts / pharmacology*
  • Plant Leaves / chemistry

Substances

  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Antioxidants
  • Hypoglycemic Agents
  • Phenols
  • Phytochemicals
  • Phytosterols
  • Plant Extracts