Physical and Biological Properties of a High-Plasticity Tricalcium Silicate Cement

Biomed Res Int. 2018 Nov 27:2018:8063262. doi: 10.1155/2018/8063262. eCollection 2018.

Abstract

Introduction: Mineral Trioxide Aggregate (MTA) is a tricalcium-based silicate, dicalcium silicate matrix. Despite its good biologic properties, some clinicians still claim to have difficulties in handling MTA after its preparation due to its sandy consistency. The aim of the present study was to evaluate the physicochemical properties and cytotoxicity of MTA Repair HP (Angelus, Londrina, PR, Brazil) compared with MTA Angelus (Angelus, Londrina, PR, Brazil).

Materials and method: The properties assessed were particle size, setting time, flow, film thickness, radiopacity, water solubility, compressive strength, and cytotoxicity. Statistical analysis was performed considering p < 0.05 as statistically significant.

Results: For radiopacity, water absorption and solubility MTA Repair HP were statistically similar to MTA Angelus. The MTA Angelus had statistically different film thickness values, higher than MTA Repair HP (p < 0.05). Besides, MTA Angelus showed a lower and statistically different compressive strength after 28 days than MTA Repair HP (p<0.05). Additionally, MTA Repair HP set more slowly (p < 0.05). Relative to cell viability, MTA Repair HP was statistically similar to MTA Angelus after 24 and 48 h in cell viability.

Conclusions: The MTA Repair HP presented similar cell viability, lower film thickness, higher flow, setting time, and compressive strength values after 28 days than MTA Angelus. In general, the MTA Repair HP presented physicochemical and biological properties similar to the MTA Angelus.

MeSH terms

  • Animals
  • Bone Cements* / chemistry
  • Bone Cements* / pharmacology
  • Calcium Compounds* / chemistry
  • Calcium Compounds* / pharmacology
  • Cell Line
  • Cell Survival / drug effects
  • Materials Testing*
  • Mice
  • Silicates* / chemistry
  • Silicates* / pharmacology

Substances

  • Bone Cements
  • Calcium Compounds
  • Silicates
  • tricalcium silicate