Roseomonas mucosa infective endocarditis in patient with systemic lupus erythematosus: case report and review of literature

BMC Infect Dis. 2019 Feb 12;19(1):140. doi: 10.1186/s12879-019-3774-0.

Abstract

Background: Roseomonas mucosa, as a Gram-negative coccobacilli, is an opportunistic pathogen that has rarely been reported in human infections. Here we describe a case of bacteremia in an infective endocarditis patient with systemic lupus erythematosus (SLE).

Case presentations: A 44-year-old female patient with SLE suffered bacteremia caused by Roseomonas mucosa complicated with infective endocarditis (IE). The patient started on treatment with piperacillin-tazobactam and levofloxacin against Roseomonas mucosa, which was switched after 4 days to meropenem and amikacin for an additional 2 weeks. She had a favorable outcome with a 6-week course of intravenous antibiotic therapy.

Discussion and conclusions: Roseomonas mucosa is rarely reported in IE patients; therefore, we report the case in order to improve our ability to identify this pathogen and expand the range of known bacterial causes of infective endocarditis.

Keywords: Bacteremia; Case report; Infective endocarditis; Roseomonas mucosa; Systemic lupus erythematosus.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Amikacin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / complications
  • Bacteremia / drug therapy
  • Bacteremia / microbiology
  • Endocarditis / complications
  • Endocarditis, Bacterial / complications*
  • Endocarditis, Bacterial / drug therapy
  • Endocarditis, Bacterial / microbiology
  • Female
  • Gram-Negative Bacterial Infections / complications*
  • Gram-Negative Bacterial Infections / drug therapy
  • Gram-Negative Bacterial Infections / microbiology
  • Humans
  • Levofloxacin / therapeutic use
  • Lupus Erythematosus, Systemic / complications*
  • Methylobacteriaceae*
  • Piperacillin, Tazobactam Drug Combination / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Piperacillin, Tazobactam Drug Combination
  • Levofloxacin
  • Amikacin