Feasibility Study of a Microfluidic Solenoid for Discrete Quantitation of Magnetized Cells

IEEE Trans Nanobioscience. 2019 Apr;18(2):240-243. doi: 10.1109/TNB.2019.2905506. Epub 2019 Mar 15.

Abstract

In this paper, a cell quantitation system is proposed based on a new microfluidic solenoid design. The design is simulated in COMSOL and a scaled version of the prototype is built and the induced voltage due to the passage of a magnetic material is measured using a low-noise amplifier and converted to a digital signal using a DSP chip. The simulation results show approximately 16-nV induced voltage across the solenoid and the measurement results for a scaled version of the solenoid outputs 125-mV peak voltage. A microfluidic fabrication process demonstrates a successful prototype of a microfluidic solenoid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Count
  • Computer Simulation
  • Equipment Design
  • Feasibility Studies
  • Lab-On-A-Chip Devices*
  • Magnetic Phenomena
  • Mice
  • Microfluidics
  • RAW 264.7 Cells
  • Software