Composition and biological activities of the essential oil from a Sicilian accession of Prangos ferulacea (L.) Lindl

Nat Prod Res. 2021 Mar;35(5):733-743. doi: 10.1080/14786419.2019.1598996. Epub 2019 Apr 8.

Abstract

Prangos ferulacea (L.) Lindl. (Fam. Apiaceae), is an orophilous species of eastern Mediterranean and western Asia which possesses several biological properties, which are worthy of exploitation in different fields. With the aim to provide new insights into the phytochemistry and pharmacology of this species, a local accession growing in Sicily (South Italy) was investigated as well. Notably, the P. ferulacea essential oil chemical composition and the antioxidant, anti-acetylcholinesterase (AChE) and cytotoxic activities have been studied. This analysis allowed to identify a new chemotype and to report good biological results for this oil.

Keywords: Apiaceae; Prangos ferulacea; biological activities; essential oil.

MeSH terms

  • Antioxidants / pharmacology
  • Apiaceae / chemistry*
  • Cell Death / drug effects
  • Cell Line, Tumor
  • Cholinesterase Inhibitors / pharmacology
  • Ecotype*
  • Humans
  • Inhibitory Concentration 50
  • Oils, Volatile / chemistry*
  • Oils, Volatile / pharmacology*
  • Plant Extracts / chemistry
  • Sicily

Substances

  • Antioxidants
  • Cholinesterase Inhibitors
  • Oils, Volatile
  • Plant Extracts