Proposal of a two-step process for the diagnosis of sepsis-induced disseminated intravascular coagulation

J Thromb Haemost. 2019 Aug;17(8):1265-1268. doi: 10.1111/jth.14482. Epub 2019 Jun 5.

Authors

Toshiaki Iba¹, Jerrold H Levy², Kazuma Yamakawa³, Jecko Thachil⁴, Theodore E Warkentin⁵, Marcel Levi⁶; Scientific and Standardization Committee on DIC of the International Society on Thrombosis and Haemostasis

Affiliations

¹ Department of Emergency and Disaster Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
² Department of Anesthesiology, Critical Care, and Surgery, Duke University School of Medicine, Durham, North Carolina.
³ Division of Trauma and Surgical Critical Care, Osaka General Medical Center, Osaka, Japan.
⁴ Department of Haematology, Manchester Royal Infirmary, Manchester, UK.
⁵ Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
⁶ Department of Medicine, University College London Hospitals NHS Foundation Trust, London, UK.

PMID: 31099127
DOI: 10.1111/jth.14482

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anticoagulants / therapeutic use
Biomarkers / blood
Blood Coagulation* / drug effects
Disseminated Intravascular Coagulation / blood
Disseminated Intravascular Coagulation / diagnosis*
Disseminated Intravascular Coagulation / drug therapy
Disseminated Intravascular Coagulation / etiology
Early Diagnosis
Fibrin Fibrinogen Degradation Products / analysis
Fibrinogen / analysis
Humans
International Normalized Ratio*
Organ Dysfunction Scores
Platelet Count*
Predictive Value of Tests
Prothrombin Time
Reproducibility of Results
Sepsis / blood
Sepsis / complications
Sepsis / diagnosis*
Sepsis / drug therapy
Workflow

Substances

Anticoagulants
Biomarkers
Fibrin Fibrinogen Degradation Products
fibrin fragment D
Fibrinogen

Grants and funding