The Impact of Diet on Breast Cancer Outcomes

Curr Nutr Rep. 2019 Sep;8(3):212-221. doi: 10.1007/s13668-019-00278-0.

Abstract

Purpose of review: Breast cancer is the most common cancer in women, yet conclusive evidence of the effects of dietary modification in breast cancer survivors is lacking. Here, we summarize the literature and highlight important data regarding the association between dietary interventions and breast cancer outcomes.

Recent findings: Long-term follow-up and secondary analysis of the Women's Health Initiative study demonstrated a significant improvement in overall survival for women who were randomized to the low-fat diet pattern compared with those in the usual-diet group. Dietary quality as measured by Healthy Eating Index score was also associated with both a decrease in cancer-specific mortality and overall mortality. Despite current evidence on the role of diet and nutrition in breast cancer outcomes, conclusive data to translate current findings to clinical practice is lacking and requires multidisciplinary prospective research to advance the field.

Keywords: Breast cancer; Breast cancer survivors; Diet intervention; Diet quality; High-quality diet; Low-fat diet; Mortality.

Publication types

  • Review

MeSH terms

  • Body Weight
  • Breast Neoplasms / diet therapy*
  • Breast Neoplasms / mortality*
  • Cancer Survivors
  • Diet*
  • Diet, Fat-Restricted
  • Diet, Healthy
  • Female
  • Humans
  • Incidence
  • Inflammation
  • Survivors
  • Weight Loss