Blood transcriptome and clonal T-cell correlates of response and non-response to eltrombopag therapy in a cohort of patients with chronic immune thrombocytopenia

Haematologica. 2020 Mar;105(3):e129-e132. doi: 10.3324/haematol.2019.226688. Epub 2019 Jul 11.

Authors

Haiyu Zhang¹, Bing M Zhang¹, Xiangqian Guo^{1

2}, Liwen Xu¹, Xiaoqing You¹, Robert B West¹, James B Bussel³, James L Zehnder⁴

Affiliations

¹ Department of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.
² Department of Preventive Medicine, School of Basic Medical Sciences, Henan University, Kaifeng, China.
³ Platelet Disorders Center, Department of Pediatrics, Weill-Cornell Medicine, New York, NY, USA.
⁴ Department of Pathology, School of Medicine, Stanford University, Stanford, CA, USA zehnder@stanford.edu.

No abstract available

Publication types

Letter

MeSH terms

Benzoates / therapeutic use
Humans
Hydrazines / therapeutic use
Purpura, Thrombocytopenic, Idiopathic* / drug therapy
Purpura, Thrombocytopenic, Idiopathic* / genetics
Pyrazoles
T-Lymphocytes
Transcriptome

Substances

Benzoates
Hydrazines
Pyrazoles
eltrombopag