RETRACTED: Silencing circANKRD36 protects H9c2 cells against lipopolysaccharide-induced injury via up-regulating miR-138

Exp Mol Pathol. 2019 Dec:111:104300. doi: 10.1016/j.yexmp.2019.104300. Epub 2019 Aug 20.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. Following the concerns raised about the background pattern of the Western Blots from Figures 1C and 3D, the corresponding author has contacted the journal to request the retraction of the article. Given the comments of Dr Elisabeth Bik regarding this article “This paper belongs to a set of over 400 papers (as per February 2020) that share very similar Western blots with tadpole-like shaped bands, the same background pattern, and striking similarities in title structures, paper layout, bar graph design, and - in a subset - flow cytometry panels”, the journal requested the authors to provide the raw data. However, the authors were not able to fulfil this request and therefore the Editor-in-Chief decided to retract the article.

Keywords: H9c2 cells; Lipopolysaccharide; circANKRD36; miR-138; p38MAPK/NF-κB pathway.

Publication types

  • Retracted Publication

MeSH terms

  • Animals
  • Apoptosis
  • Cell Survival
  • Cytokines
  • Gene Expression Regulation
  • Heart Ventricles / drug effects
  • Heart Ventricles / metabolism
  • Heart Ventricles / pathology*
  • Inflammation / chemically induced
  • Inflammation / genetics
  • Inflammation / pathology
  • Inflammation / prevention & control*
  • Lipopolysaccharides / toxicity*
  • MicroRNAs / genetics*
  • Myocarditis / chemically induced
  • Myocarditis / genetics
  • Myocarditis / pathology
  • Myocarditis / prevention & control*
  • Myocytes, Cardiac / drug effects
  • Myocytes, Cardiac / metabolism
  • Myocytes, Cardiac / pathology*
  • NF-kappa B / genetics
  • NF-kappa B / metabolism
  • Protective Agents / metabolism
  • RNA, Circular / genetics*
  • Rats
  • Signal Transduction
  • Up-Regulation
  • p38 Mitogen-Activated Protein Kinases / genetics
  • p38 Mitogen-Activated Protein Kinases / metabolism

Substances

  • Cytokines
  • Lipopolysaccharides
  • MIRN138 microRNA, rat
  • MicroRNAs
  • NF-kappa B
  • Protective Agents
  • RNA, Circular
  • p38 Mitogen-Activated Protein Kinases