Out-of-time-ordered correlators (OTOCs) have been proposed as a probe of chaos in quantum mechanics, on the basis of their short-time exponential growth found in some particular setups. However, it has been seen that this behavior is not universal. Therefore, we query other quantum chaos manifestations arising from the OTOCs, and we thus study their long-time behavior in systems of completely different nature: quantum maps, which are the simplest chaotic one-body system, and spin chains, which are many-body systems without a classical limit. It is shown that studying the long-time regime of the OTOCs it is possible to detect and gauge the transition between integrability and chaos, and we benchmark the transition with other indicators of quantum chaos based on the spectra and the eigenstates of the systems considered. For systems with a classical analog, we show that the proposed OTOC indicators have a very high accuracy that allow us to detect subtle features along the integrability-to-chaos transition.