Accurate detection of atrial fibrillation from 12-lead ECG using deep neural network

Comput Biol Med. 2020 Jan:116:103378. doi: 10.1016/j.compbiomed.2019.103378. Epub 2019 Aug 2.

Abstract

Atrial fibrillation (AF) is the most common heart arrhythmia, and 12-lead electrocardiogram (ECG) is regarded as the gold standard for AF diagnosis. Highly accurate diagnosis of AF based on 12-lead ECG is valuable and remains challenging. In this paper, we proposed a novel method with high accuracy for AF detection based on deep learning. The proposed method constructed a novel one-dimensional deep densely connected neural network (DDNN) to detect AF in ECG waveforms with a length of 10s. A large set of 16,557 12-lead ECG recordings collected from multiple hospitals and wearable ECG devices were used to evaluate the performance of the DDNN. In the test dataset (3312 12-lead ECG recordings), the DDNN obtained high performance with an accuracy of 99.35 ± 0.26%, a sensitivity of 99.19 ± 0.31%, and a specificity of 99.44 ± 0.17%. Its high performance and automatic nature both demonstrate that the proposed network has a great potential to be applied to clinical computer-aided diagnosis of AF or future screening of AF in wearable devices.

Keywords: 12-Lead ECG; Atrial fibrillation detection; Deep learning; Densely connected neural network.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Atrial Fibrillation / diagnosis*
  • Deep Learning*
  • Diagnosis, Computer-Assisted
  • Electrocardiography / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neural Networks, Computer
  • Signal Processing, Computer-Assisted*