Reproductive outcome of a complete septate uterus after hysteroscopic metroplasty

J Int Med Res. 2020 Mar;48(3):300060519893836. doi: 10.1177/0300060519893836. Epub 2019 Dec 19.

Abstract

Objective: This study aimed to evaluate the reproductive outcomes of patients who underwent hysteroscopic metroplasty for correction of a complete septate uterus.

Methods: The study population comprised 92 women with complete septate uteri. Hysteroscopic metroplasty and laparoscopy were performed simultaneously in these patients. The postoperative reproductive outcome of each patient was evaluated.

Results: In the primary infertility group, there were 32 (40%) pregnancies. In the abortion group, the number of miscarriages decreased from 68 (94.44%) to 5 (10.42%), while the number of live births increased from 1 (1.39%) to 42 (87.50%) after resection compared with before resection. The cumulative probability of pregnancy and that of live-birth pregnancy in the abortion group were significantly higher than those in the primary infertility group after surgery. Furthermore, resection of the cervical septum resulted in a significantly higher cumulative probability of live birth compared with preservation of the cervical septum.

Conclusion: Hysteroscopic uterine metroplasty may improve the reproductive performance of a septate uterus. Resection of the cervical septum may increase the probability of a live-birth pregnancy for patients with a cervical septum, and this procedure could be recommended for cases of a complete uterine septum.

Keywords: Septate uterus; abortion; hysteroscopic metroplasty; live birth; miscarriage; pregnancy.

MeSH terms

  • Abortion, Spontaneous*
  • Cervix Uteri / surgery
  • Female
  • Humans
  • Hysteroscopy*
  • Infertility, Female* / etiology
  • Infertility, Female* / surgery
  • Live Birth
  • Pregnancy
  • Pregnancy Outcome
  • Uterus* / abnormalities
  • Uterus* / surgery