Advances and Impact of Antioxidant Hydrogel in Chronic Wound Healing

Adv Healthc Mater. 2020 Mar;9(5):e1901502. doi: 10.1002/adhm.201901502. Epub 2020 Jan 24.

Abstract

The accelerating and thorough treatment of chronic wounds still represents a major unmet medical need owing to the complex symptoms resulting from metabolic disorder of the wound microenvironment. Although numerous strategies and bioactive hydrogels are developed, an effective and widely used method of chronic wound treatment remains a bottleneck. With the aim to accelerate chronic wound healing, many hydrogel dressings with antioxidant functions have emerged and are proven to accelerate wound healing, especially for chronic wound repair. The new strategy in chronic wound treatment brought by antioxidant hydrogels is of great significance to human health. Here, the application of antioxidant hydrogels in the repair of chronic wounds is discussed systematically, aiming to provide an important theoretical reference for the further breakthrough of chronic wound healing.

Keywords: antioxidants; chronic wound healing; hydrogels.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antioxidants*
  • Bandages
  • Humans
  • Hydrogels*
  • Wound Healing

Substances

  • Antioxidants
  • Hydrogels