Organic Room Temperature Phosphorescence Materials for Biomedical Applications

Chem Asian J. 2020 Apr 1;15(7):947-957. doi: 10.1002/asia.201901658. Epub 2020 Feb 26.

Abstract

Organic room temperature phosphorescence (RTP) materials have drawn increasing attention due to their unique features, especially the long emission lifetime for applications in biomedicine. In this review, we provide an overview of the recent developments of organic RTP materials applied in the biomedicine field. First, we introduce the basic mechanism of phosphorescence and subsequently we present various strategies of modulating the lifetime and efficiency of room temperature organic phosphorescence. Next, we summarize the progress of organic RTP materials in biological applications, including bioimaging, anti-cancer and antibacterial therapies. Finally, we provide an outlook with regard to the challenges and future perspectives in the field.

Keywords: antibacterial; bioimaging; nanoparticles; organic phosphorescence; photodynamic therapy.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / therapeutic use
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / therapeutic use
  • Diagnostic Imaging / methods
  • Humans
  • Luminescence
  • Luminescent Agents / pharmacology*
  • Luminescent Agents / therapeutic use
  • Luminescent Measurements / methods*
  • Temperature*

Substances

  • Anti-Bacterial Agents
  • Antineoplastic Agents
  • Luminescent Agents