Emerging applications of paper-based analytical devices for drug analysis: A review

Anal Chim Acta. 2020 Jun 15:1116:70-90. doi: 10.1016/j.aca.2020.03.013. Epub 2020 Mar 11.

Abstract

The use of paper microfluidics to perform chemical measurements for various analytical applications has gained interest over the last decade. One of the growing applications of these platforms is for the qualitative and quantitative determination of drugs. The low cost and self-pumping ability of paper microfluidics are attractive for developing analytical tools capable of on-site drug screening. This review aims to present the unique features of microfluidic paper-based analytical devices (μPADs) that offer advantages to pharmaceutical analysis and evaluate the state-of-the-art technologies and applications of the platform for drug analysis in research and real-world settings. The current challenges and potential future directions of the field are also highlighted.

Keywords: Drug analysis; Microfluidic paper-based analytical device (μPAD); Paper microfluids.

Publication types

  • Review

MeSH terms

  • Animals
  • Counterfeit Drugs / analysis
  • Food Contamination / analysis
  • Humans
  • Lab-On-A-Chip Devices*
  • Microfluidic Analytical Techniques / instrumentation
  • Microfluidic Analytical Techniques / methods*
  • Paper*
  • Pharmaceutical Preparations / analysis*

Substances

  • Counterfeit Drugs
  • Pharmaceutical Preparations