This brief is devoted to exploring the global Mittag-Leffler (ML) synchronization problem of fractional-order memristor neural networks (FOMNNs) with leakage delay via a hybrid adaptive controller. By applying Fillipov's theory and the Lyapunov functional method, the novel algebraic sufficient condition for the global ML synchronization of FOMNNs is derived. Finally, a simulation example is presented to show the practicability of our findings.