HIV infection and COVID-19: risk factors for severe disease

AIDS. 2020 Oct 1;34(12):1771-1774. doi: 10.1097/QAD.0000000000002651.

Abstract

: We performed an observational prospective monocentric study in patients living with HIV (PLWH) diagnosed with COVID-19. Fifty-four PLWH developed COVID-19 with 14 severe (25.9%) and five critical cases (9.3%), respectively. By multivariate analysis, age, male sex, ethnic origin from sub-Saharan Africa and metabolic disorder were associated with severe or critical forms of COVID-19. Prior CD4 T cell counts did not differ between groups. No protective effect of a particular antiretroviral class was observed.

Publication types

  • Letter
  • Observational Study

MeSH terms

  • Adult
  • Africa South of the Sahara / ethnology
  • Anti-Retroviral Agents / therapeutic use
  • CD4 Lymphocyte Count
  • COVID-19
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / ethnology
  • Female
  • France / epidemiology
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • Humans
  • Logistic Models
  • Male
  • Metabolic Diseases / complications
  • Middle Aged
  • Multivariate Analysis
  • Pandemics
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / ethnology
  • Prospective Studies
  • Risk Assessment
  • Risk Factors

Substances

  • Anti-Retroviral Agents