A bi-tapered and air-gapped beam shaping assembly used for AB-BNCT

Appl Radiat Isot. 2021 Jan:167:109392. doi: 10.1016/j.apradiso.2020.109392. Epub 2020 Oct 9.

Abstract

The 7Li(p,n)7Be reaction, which leads to a soft neutron field, is often chosen as the neutron producing reaction used for accelerator-based boron neutron capture therapy (AB-BNCT). This study aims to design a compact beam shaping assembly (BSA) and auxiliary system for a 7Li(p,n)7Be reaction-based neutron source and to evaluate the relationship between the BSA design and the consequent neutron beam quality for further optimization. In this study, five types of moderator shapes for the BSA model were designed. Both the in-air and in-phantom figures of merit were considered to evaluate the performance of the BSA designs. It was found that the BSA with a bi-tapered and air-gapped design could generate a high-intensity epithermal neutron beam, which could be used to treat deep-seated brain tumors within a reasonable time.

Keywords: (7)Li(p,n)(7)Be reaction; Accelerator-based BNCT; Beam shaping assembly; Moderator.

MeSH terms

  • Boron Neutron Capture Therapy / instrumentation*
  • Brain Neoplasms / radiotherapy
  • Equipment Design*
  • Humans
  • Monte Carlo Method
  • Neutrons
  • Phantoms, Imaging