High prevalence of Afro-Caribbean ethnicity and hypoglycaemia in patients with diabetes and end stage renal disease hospitalized with COVID-19

Nephrology (Carlton). 2021 Mar;26(3):252-254. doi: 10.1111/nep.13809. Epub 2020 Nov 17.

Abstract

End stage renal disease (ESRD) is associated with a high mortality rate among patients hospitalized with COVID-19. To the best of our knowledge, there is limited data on the clinical features, ethnicity, inpatient glycaemic control and outcomes in patients with diabetes related ESRD in the literature. We report the clinical features and outcomes of 39 consecutive ESRD patients (28 on haemodialysis [HD] and 11 with renal transplant) secondary to diabetic kidney disease admitted to a university hospital with COVID-19. We observed a high prevalence of patients of Afro-Caribbean ethnicity hospitalized with COVID-19 with a 73% and 54% prevalence in renal transplant and HD groups respectively. The mortality rate of our cohort was 36%. Nearly a one-third of HD patients and one-fifth of transplant patients had hypoglycaemic events during COVID-19 hospitalization. Adjustment of diabetes treatment was frequently required. Our data highlight the importance of integrated multidisciplinary care of patients with diabetes related ESRD hospitalized with COVID-19.

Keywords: COVID-19; diabetes; end stage renal disease; ethnicity; haemodialysis; hypoglycaemia; renal transplant.

MeSH terms

  • Blood Glucose / analysis*
  • COVID-19* / epidemiology
  • COVID-19* / ethnology
  • COVID-19* / therapy
  • Caribbean Region
  • Diabetes Complications* / blood
  • Diabetes Complications* / ethnology
  • Diabetes Complications* / physiopathology
  • Ethnicity / statistics & numerical data*
  • Female
  • Humans
  • Hypoglycemia* / diagnosis
  • Hypoglycemia* / etiology
  • Kidney Failure, Chronic* / ethnology
  • Kidney Failure, Chronic* / etiology
  • Kidney Failure, Chronic* / therapy
  • Kidney Transplantation / statistics & numerical data
  • Male
  • Middle Aged
  • Needs Assessment
  • Patient Care Team
  • Renal Dialysis / statistics & numerical data*
  • Risk Factors
  • SARS-CoV-2 / isolation & purification
  • United Kingdom / epidemiology

Substances

  • Blood Glucose