Identification and characterisation of bioactive compounds from the seed kernels and hulls of Paeonia lactiflora Pall by UPLC-QTOF-MS

Rong Nie; Yiren Zhang; Qingzhe Jin; Shuang Zhang; Gangcheng Wu; Li Chen; Hui Zhang; Xingguo Wang

doi:10.1016/j.foodres.2020.109916

Identification and characterisation of bioactive compounds from the seed kernels and hulls of Paeonia lactiflora Pall by UPLC-QTOF-MS

Food Res Int. 2021 Jan:139:109916. doi: 10.1016/j.foodres.2020.109916. Epub 2020 Nov 30.

Authors

Rong Nie¹, Yiren Zhang², Qingzhe Jin¹, Shuang Zhang¹, Gangcheng Wu³, Li Chen⁴, Hui Zhang⁵, Xingguo Wang¹

Affiliations

¹ Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), China; National Engineering Research Center for Functional Food, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology, Jiangnan University, China.
² Department of Chemistry, School of Physical Sciences, University of Liverpool, UK.
³ Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), China; National Engineering Research Center for Functional Food, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology, Jiangnan University, China. Electronic address: gangcheng.wu@jiangnan.edu.cn.
⁴ Hubei Provincial Institute for Food Supervision and Test, Wuhan, China.
⁵ Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), China; National Engineering Research Center for Functional Food, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology, Jiangnan University, China. Electronic address: zhanghui@jiangnan.edu.cn.

PMID: 33509483
DOI: 10.1016/j.foodres.2020.109916

Abstract

The seed kernels and hulls of Paeonia lactiflora Pall. (Chinese peony) contain numerous bioactive compounds. We extracted monoterpene glycosides and oligostilbenes from three varieties of P. lactiflora seed kernels and hulls, and analysed the bioactive compounds in these samples. The results indicated that seed kernels contained significant concentrations of monoterpene glycosides, whilst seed hulls contained high concentrations of oligostilbene compounds. The profiles of monoterpene glycosides and oligostilbene compounds in extracts were significantly dependent on the P. lactiflora variety. Ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry and reference to literature data enabled 96 compounds to be tentatively characterised, including 24 monoterpene glycosides, 16 oligostilbene compounds, and several phenolic compounds, iridoid glycosides, diterpenoids and triterpenoids. This is the first study to find most of these compounds in P. lactiflora seed kernels and hulls. Paeoniflorin (1779.61 ± 10.33 mg/100 g) was the predominant monoterpene glycoside in seed kernels, whilst hulls had the highest concentrations of sufruticosol A (791.93 ± 25.09 mg/100 g) and trans-ε-viniferin (607.4 ± 16.22 mg/100 g). All of the results confirmed that P. lactiflora seed kernels and hulls contain substantial concentrations of natural products. These products may be useful as medicines or as ingredients in functional foods.

Keywords: Bioactive compounds; Monoterpene glycoside; Oligostilbene compound; Paeonia lactiflora Pall.; UPLC-QTOF-MS.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromatography, Liquid
Drugs, Chinese Herbal*
Glycosides
Paeonia*
Seeds

Substances

Drugs, Chinese Herbal
Glycosides