The prognostic importance of neutrophil-to-lymphocyte ratio in testicular cancer

Urologia. 2021 Aug;88(3):200-205. doi: 10.1177/0391560321993584. Epub 2021 Feb 10.

Abstract

Purpose: Testicular cancer is mostly seen in young men. We planned this study that neutrophil-lymphocyte ratio (NLR) would help us predict the prognosis of the patients, except known markers such as AFP, hCG, and LDH.

Patients and method: Between 2015 and 2020, we conducted our study on 152 patients undergoing radical orchiectomy in our clinic. We divided our patients into good, moderate, and poor prognostic groups. We also created a control group of healthy patients of similar ages. We evaluated the NLR results in preoperative peripheral blood statistically among these groups.

Results: We found a significant difference between the control group and the patient group, and between the good and moderate/poor prognostic groups for preoperative NLR.

Conclusion: This study created the opinion that preoperative NLR will help us predict the prognosis of patients.

Keywords: NLR; Testicular cancer; lymphocyte; neutrophil; prognosis.

MeSH terms

  • Humans
  • Lymphocyte Count
  • Lymphocytes
  • Male
  • Neutrophils*
  • Prognosis
  • Retrospective Studies
  • Testicular Neoplasms* / surgery