Abstract
We determined the concentration of biliprotein in plasma of rats at different times after partial hepatectomy. From the same plasma samples, we purified a liver growth factor previously characterized by our group. When we plotted the 14 points studied, a linear relationship was obtained (r = 0.999; p less than 0.001). This result, in addition to our group's recent identification of this liver growth factor as an albumin-bilirubin complex, strongly suggests that biliprotein is a liver growth factor.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Bilirubin / blood*
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Bilirubin / isolation & purification
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Bilirubin / pharmacology
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Chromatography, Ion Exchange
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Growth Substances / blood*
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Growth Substances / isolation & purification
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Growth Substances / pharmacology
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Hepatectomy
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Mice
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Rats
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Rats, Inbred Strains
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Serum Albumin / analysis*
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Serum Albumin / blood*
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Serum Albumin / isolation & purification
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Serum Albumin / pharmacology
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Serum Albumin, Human
Substances
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Growth Substances
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Serum Albumin
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albumin-bilirubin complex
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Bilirubin
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Serum Albumin, Human