Guillain-Barré syndrome associated with COVID-19: a case report study

J Neurovirol. 2021 Oct;27(5):802-805. doi: 10.1007/s13365-021-00984-y. Epub 2021 May 27.

Abstract

Acute respiratory distress syndrome (ARDS) caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is spreading around the world. Patients with coronavirus disease 2019 (COVID-19) typically present fever, cough, and respiratory illnesses. It has been revealed that the comorbidities can turn it into severe types, and the managements meet unpredicted complications. Here, we report a case of coronavirus disease 2019 (COVID-19) coincidence with confirmed acute Guillain-Barré syndrome (GBS). Ten days after admission and therapeutic process, the patient developed autonomic dysfunction. Despite respiratory support and receiving intravenous immunoglobulin, the patient died due to cardiac arrest. Albeit it is yet scientifically doubtful, there are raising concerns toward a possible association between GBS and SARS-CoV-2 infection, demonstrating potential neurological symptoms of COVID-19.

Keywords: Acute respiratory distress syndrome; COVID-19; Guillain-Barré syndrome.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • COVID-19 / complications*
  • Fatal Outcome
  • Guillain-Barre Syndrome / virology*
  • Humans
  • Male
  • SARS-CoV-2